| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PgpB-2 | bacA | XOO3671 | XOO4489 | Membrane-associated phospholipid phosphatase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.911 |
| PgpB-2 | uppS | XOO3671 | XOO1972 | Membrane-associated phospholipid phosphatase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.907 |
| XOO1969 | cdsA | XOO1969 | XOO1971 | Predicted membrane-associated Zn-dependent proteases 1; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Phosphatidate cytidylyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDS family. | 0.898 |
| XOO1969 | dxr | XOO1969 | XOO1970 | Predicted membrane-associated Zn-dependent proteases 1; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.891 |
| XOO1969 | frr | XOO1969 | XOO1973 | Predicted membrane-associated Zn-dependent proteases 1; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.859 |
| XOO1969 | oma | XOO1969 | XOO1968 | Predicted membrane-associated Zn-dependent proteases 1; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Outer membrane antigen; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.957 |
| XOO1969 | pyrH | XOO1969 | XOO1974 | Predicted membrane-associated Zn-dependent proteases 1; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.675 |
| XOO1969 | uppS | XOO1969 | XOO1972 | Predicted membrane-associated Zn-dependent proteases 1; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.925 |
| bacA | PgpB-2 | XOO4489 | XOO3671 | Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | Membrane-associated phospholipid phosphatase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.911 |
| bacA | uppS | XOO4489 | XOO1972 | Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.933 |
| cdsA | XOO1969 | XOO1971 | XOO1969 | Phosphatidate cytidylyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDS family. | Predicted membrane-associated Zn-dependent proteases 1; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.898 |
| cdsA | dxr | XOO1971 | XOO1970 | Phosphatidate cytidylyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDS family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.960 |
| cdsA | frr | XOO1971 | XOO1973 | Phosphatidate cytidylyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDS family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.873 |
| cdsA | oma | XOO1971 | XOO1968 | Phosphatidate cytidylyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDS family. | Outer membrane antigen; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.792 |
| cdsA | pyrH | XOO1971 | XOO1974 | Phosphatidate cytidylyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDS family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.825 |
| cdsA | uppS | XOO1971 | XOO1972 | Phosphatidate cytidylyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDS family. | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.992 |
| dxr | XOO1969 | XOO1970 | XOO1969 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Predicted membrane-associated Zn-dependent proteases 1; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.891 |
| dxr | cdsA | XOO1970 | XOO1971 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Phosphatidate cytidylyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDS family. | 0.960 |
| dxr | frr | XOO1970 | XOO1973 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.890 |
| dxr | ispA | XOO1970 | XOO3299 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Geranyltranstransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the FPP/GGPP synthase family. | 0.497 |