| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AraD | mtnC | XOO2139 | XOO2137 | Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | Enolase-phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.999 |
| AraD | mtnD | XOO2139 | XOO2138 | Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | Dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.991 |
| AraD | yhdG | XOO2139 | XOO2140 | Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | Cationic amino acid transporter; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.575 |
| TolB | kefB-2 | XOO0409 | XOO2188 | Periplasmic component of the Tol biopolymer transport system; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Transport protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.604 |
| TolB | pheA-2 | XOO0409 | XOO2387 | Periplasmic component of the Tol biopolymer transport system; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Prephenate dehydratase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.482 |
| TolB | queF | XOO0409 | XOO4185 | Periplasmic component of the Tol biopolymer transport system; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.610 |
| TolB | yhdG | XOO0409 | XOO2140 | Periplasmic component of the Tol biopolymer transport system; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Cationic amino acid transporter; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.607 |
| kefB-2 | TolB | XOO2188 | XOO0409 | Transport protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Periplasmic component of the Tol biopolymer transport system; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.604 |
| kefB-2 | pheA-2 | XOO2188 | XOO2387 | Transport protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Prephenate dehydratase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.504 |
| kefB-2 | queF | XOO2188 | XOO4185 | Transport protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.636 |
| kefB-2 | tolB | XOO2188 | XOO1668 | Transport protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | TolB protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.604 |
| kefB-2 | yhdG | XOO2188 | XOO2140 | Transport protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Cationic amino acid transporter; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.627 |
| mtnC | AraD | XOO2137 | XOO2139 | Enolase-phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.999 |
| mtnC | mtnD | XOO2137 | XOO2138 | Enolase-phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | Dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.998 |
| mtnC | yhdG | XOO2137 | XOO2140 | Enolase-phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | Cationic amino acid transporter; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.570 |
| mtnD | AraD | XOO2138 | XOO2139 | Dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.991 |
| mtnD | mtnC | XOO2138 | XOO2137 | Dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | Enolase-phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.998 |
| mtnD | yhdG | XOO2138 | XOO2140 | Dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | Cationic amino acid transporter; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.654 |
| pheA | pheA-2 | XOO0734 | XOO2387 | Prephenate dehydratase; Catalyzes the Claisen rearrangement of chorismate to prephenate. | Prephenate dehydratase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.970 |
| pheA | yhdG | XOO0734 | XOO2140 | Prephenate dehydratase; Catalyzes the Claisen rearrangement of chorismate to prephenate. | Cationic amino acid transporter; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.732 |