| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fumB | fumC | XOO2336 | XOO2057 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.978 |
| fumB | sdhA | XOO2336 | XOO2308 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate dehydrogenase flavoprotein subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.996 |
| fumB | sdhB | XOO2336 | XOO2307 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate dehydrogenase iron-sulfur protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.994 |
| fumB | sdhC | XOO2336 | XOO2310 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate dehydrogenase membrane anchor subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.984 |
| fumB | sdhD | XOO2336 | XOO2309 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate dehydrogenase membrane anchor subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.979 |
| fumB | sucC | XOO2336 | XOO1593 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.793 |
| fumB | sucD | XOO2336 | XOO1594 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.682 |
| fumC | fumB | XOO2057 | XOO2336 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.978 |
| fumC | nuoE | XOO2057 | XOO3232 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | NADH-ubiquinone oxidoreductase NQO2 subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.447 |
| fumC | nuoF | XOO2057 | XOO3230 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | NADH-ubiquinone oxidoreductase NQO1 subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. | 0.515 |
| fumC | petA | XOO2057 | XOO2762 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Ubiquinol cytochrome C oxidoreductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | 0.416 |
| fumC | sdhA | XOO2057 | XOO2308 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Succinate dehydrogenase flavoprotein subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.998 |
| fumC | sdhB | XOO2057 | XOO2307 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Succinate dehydrogenase iron-sulfur protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.965 |
| fumC | sdhC | XOO2057 | XOO2310 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Succinate dehydrogenase membrane anchor subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.957 |
| fumC | sdhD | XOO2057 | XOO2309 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Succinate dehydrogenase membrane anchor subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.917 |
| fumC | sucC | XOO2057 | XOO1593 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.714 |
| fumC | sucD | XOO2057 | XOO1594 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.764 |
| nuoE | fumC | XOO3232 | XOO2057 | NADH-ubiquinone oxidoreductase NQO2 subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.447 |
| nuoE | nuoF | XOO3232 | XOO3230 | NADH-ubiquinone oxidoreductase NQO2 subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | NADH-ubiquinone oxidoreductase NQO1 subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. | 0.999 |
| nuoE | petA | XOO3232 | XOO2762 | NADH-ubiquinone oxidoreductase NQO2 subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Ubiquinol cytochrome C oxidoreductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | 0.977 |