| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cca | folK | XOO3900 | XOO2365 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.622 |
| cca | ribD | XOO3900 | XOO3856 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.476 |
| folB | folC | XOO4124 | XOO3679 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Folylpolyglutamate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.715 |
| folB | folE | XOO4124 | XOO4600 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.967 |
| folB | folK | XOO4124 | XOO2365 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.993 |
| folB | folK-2 | XOO4124 | XOO3933 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.992 |
| folB | folP | XOO4124 | XOO2948 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.997 |
| folB | ribD | XOO4124 | XOO3856 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.723 |
| folC | folB | XOO3679 | XOO4124 | Folylpolyglutamate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.715 |
| folC | folE | XOO3679 | XOO4600 | Folylpolyglutamate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | GTP cyclohydrolase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.715 |
| folC | folK | XOO3679 | XOO2365 | Folylpolyglutamate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.743 |
| folC | folK-2 | XOO3679 | XOO3933 | Folylpolyglutamate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.523 |
| folC | folP | XOO3679 | XOO2948 | Folylpolyglutamate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.997 |
| folC | panC | XOO3679 | XOO2363 | Folylpolyglutamate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.411 |
| folC | ribD | XOO3679 | XOO3856 | Folylpolyglutamate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.618 |
| folE | folB | XOO4600 | XOO4124 | GTP cyclohydrolase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.967 |
| folE | folC | XOO4600 | XOO3679 | GTP cyclohydrolase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Folylpolyglutamate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.715 |
| folE | folK | XOO4600 | XOO2365 | GTP cyclohydrolase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.987 |
| folE | folK-2 | XOO4600 | XOO3933 | GTP cyclohydrolase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.867 |
| folE | folP | XOO4600 | XOO2948 | GTP cyclohydrolase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.984 |