| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RseA | clpP | XOO1850 | XOO1033 | Negative regulator of sigma E activity; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.555 |
| RseA | clpS | XOO1850 | XOO2554 | Negative regulator of sigma E activity; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.480 |
| RseA | clpX | XOO1850 | XOO1034 | Negative regulator of sigma E activity; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | ATP-dependent Clp protease ATP binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.653 |
| RseA | sspB | XOO1850 | XOO2758 | Negative regulator of sigma E activity; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Stringent starvation protein B; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.896 |
| apaH | ftsB | XOO3750 | XOO2962 | Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Conserved hypothetical protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.702 |
| apaH | ftsQ | XOO3750 | XOO4907 | Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.711 |
| apaH | smpA | XOO3750 | XOO2026 | Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.549 |
| apaH | sspA | XOO3750 | XOO2759 | Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Stringent starvation protein A; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.703 |
| apaH | sspB | XOO3750 | XOO2758 | Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Stringent starvation protein B; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.735 |
| clpP | RseA | XOO1033 | XOO1850 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Negative regulator of sigma E activity; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.555 |
| clpP | clpS | XOO1033 | XOO2554 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.910 |
| clpP | clpX | XOO1033 | XOO1034 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease ATP binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.999 |
| clpP | sspB | XOO1033 | XOO2758 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Stringent starvation protein B; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.924 |
| clpS | RseA | XOO2554 | XOO1850 | Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | Negative regulator of sigma E activity; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.480 |
| clpS | clpP | XOO2554 | XOO1033 | Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.910 |
| clpS | clpX | XOO2554 | XOO1034 | Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | ATP-dependent Clp protease ATP binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.846 |
| clpS | sspB | XOO2554 | XOO2758 | Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | Stringent starvation protein B; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.882 |
| clpX | RseA | XOO1034 | XOO1850 | ATP-dependent Clp protease ATP binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Negative regulator of sigma E activity; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.653 |
| clpX | clpP | XOO1034 | XOO1033 | ATP-dependent Clp protease ATP binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.999 |
| clpX | clpS | XOO1034 | XOO2554 | ATP-dependent Clp protease ATP binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.846 |