| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PcbC | rluC | XOO3248 | XOO3072 | Isopenicillin N synthase and related dioxygenases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the iron/ascorbate-dependent oxidoreductase family. | Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.690 |
| SpoU | mraW | XOO2084 | XOO3833 | rRNA methylases; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | Cell division protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.466 |
| SpoU | rluC | XOO2084 | XOO3072 | rRNA methylases; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.584 |
| SpoU | rplC | XOO2084 | XOO3584 | rRNA methylases; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.749 |
| SpoU | rplO | XOO2084 | XOO3563 | rRNA methylases; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.746 |
| SpoU | rplU | XOO2084 | XOO1620 | rRNA methylases; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.668 |
| SpoU | yhbZ | XOO2084 | XOO1622 | rRNA methylases; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.441 |
| SpoU-2 | rluC | XOO3388 | XOO3072 | rRNA methylases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.543 |
| SpoU-2 | rplC | XOO3388 | XOO3584 | rRNA methylases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.703 |
| SpoU-2 | rplO | XOO3388 | XOO3563 | rRNA methylases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.775 |
| SpoU-2 | rplU | XOO3388 | XOO1620 | rRNA methylases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.668 |
| SpoU-2 | yhbZ | XOO3388 | XOO1622 | rRNA methylases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.510 |
| mraW | SpoU | XOO3833 | XOO2084 | Cell division protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | rRNA methylases; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 0.466 |
| mraW | rluC | XOO3833 | XOO3072 | Cell division protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.550 |
| mraW | rplU | XOO3833 | XOO1620 | Cell division protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.414 |
| mraW | yhbZ | XOO3833 | XOO1622 | Cell division protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.541 |
| rluC | PcbC | XOO3072 | XOO3248 | Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Isopenicillin N synthase and related dioxygenases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the iron/ascorbate-dependent oxidoreductase family. | 0.690 |
| rluC | SpoU | XOO3072 | XOO2084 | Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | rRNA methylases; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 0.584 |
| rluC | SpoU-2 | XOO3072 | XOO3388 | Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | rRNA methylases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.543 |
| rluC | mraW | XOO3072 | XOO3833 | Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Cell division protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.550 |