| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XOO1819 | asd | XOO1819 | XOO3259 | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.962 |
| XOO1819 | dapA | XOO1819 | XOO2923 | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Dihydroxydipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.920 |
| XOO1819 | gltB | XOO1819 | XOO0177 | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Glutamate synthase, alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.606 |
| XOO1819 | lysA-2 | XOO1819 | XOO1433 | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Diaminopimelate decarboxylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.693 |
| XOO1819 | metB-2 | XOO1819 | XOO1818 | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Cystathionine gamma-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.972 |
| XOO1819 | metH2 | XOO1819 | XOO2073 | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.950 |
| XOO1819 | metL | XOO1819 | XOO2242 | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Aspartokinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.944 |
| aroC | asd | XOO3261 | XOO3259 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.814 |
| aroC | lysA-2 | XOO3261 | XOO1433 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Diaminopimelate decarboxylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.510 |
| aroC | metL | XOO3261 | XOO2242 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Aspartokinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.629 |
| asd | XOO1819 | XOO3259 | XOO1819 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.962 |
| asd | aroC | XOO3259 | XOO3261 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.814 |
| asd | dapA | XOO3259 | XOO2923 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydroxydipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.978 |
| asd | dapA-2 | XOO3259 | XOO3137 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate synthetase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the DapA family. | 0.774 |
| asd | dapF | XOO3259 | XOO3997 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.788 |
| asd | gltB | XOO3259 | XOO0177 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Glutamate synthase, alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.747 |
| asd | lysA-2 | XOO3259 | XOO1433 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate decarboxylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.989 |
| asd | metB-2 | XOO3259 | XOO1818 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Cystathionine gamma-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.767 |
| asd | metH2 | XOO3259 | XOO2073 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.794 |
| asd | metL | XOO3259 | XOO2242 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Aspartokinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.999 |