| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CspR | rlmH | XOO4206 | XOO3322 | tRNA/rRNA methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.578 |
| XOO2509 | hslR | XOO2509 | XOO1330 | N6-adenine-specific methylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Heat shock protein 15; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.406 |
| XOO2509 | nadD | XOO2509 | XOO3326 | N6-adenine-specific methylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.404 |
| XOO2509 | rlmH | XOO2509 | XOO3322 | N6-adenine-specific methylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.640 |
| dacC | rlmH | XOO3956 | XOO3322 | Penicillin-binding protein 6; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the peptidase S11 family. | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.470 |
| hslR | XOO2509 | XOO1330 | XOO2509 | Heat shock protein 15; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | N6-adenine-specific methylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.406 |
| hslR | rlmH | XOO1330 | XOO3322 | Heat shock protein 15; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.541 |
| hslR | rsfS | XOO1330 | XOO3325 | Heat shock protein 15; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.651 |
| nadD | XOO2509 | XOO3326 | XOO2509 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | N6-adenine-specific methylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.404 |
| nadD | rlmH | XOO3326 | XOO3322 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.710 |
| nadD | rsfS | XOO3326 | XOO3325 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.932 |
| prmA | rlmH | XOO0552 | XOO3322 | Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.596 |
| rlmH | CspR | XOO3322 | XOO4206 | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | tRNA/rRNA methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.578 |
| rlmH | XOO2509 | XOO3322 | XOO2509 | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | N6-adenine-specific methylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.640 |
| rlmH | dacC | XOO3322 | XOO3956 | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Penicillin-binding protein 6; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the peptidase S11 family. | 0.470 |
| rlmH | hslR | XOO3322 | XOO1330 | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Heat shock protein 15; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.541 |
| rlmH | nadD | XOO3322 | XOO3326 | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.710 |
| rlmH | prmA | XOO3322 | XOO0552 | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.596 |
| rlmH | rlmL | XOO3322 | XOO2438 | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Conserved hypothetical protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.571 |
| rlmH | rsfS | XOO3322 | XOO3325 | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.926 |