| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ThiE | ThiS | XOO3816 | XOO3371 | Thiamine monophosphate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Nudix hydrolase family. | Sulfur transfer protein involved in thiamine biosynthesis; With ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate. | 0.799 |
| ThiE | dxs | XOO3816 | XOO2017 | Thiamine monophosphate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Nudix hydrolase family. | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.416 |
| ThiE | moeB-2 | XOO3816 | XOO2514 | Thiamine monophosphate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Nudix hydrolase family. | Molybdopterin biosynthesis protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.871 |
| ThiE | thiC | XOO3816 | XOO0947 | Thiamine monophosphate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Nudix hydrolase family. | Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.846 |
| ThiE | thiD | XOO3816 | XOO2928 | Thiamine monophosphate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Nudix hydrolase family. | Phosphomethylpyrimidine kinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.900 |
| ThiE | thiE | XOO3816 | XOO1123 | Thiamine monophosphate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Nudix hydrolase family. | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.751 |
| ThiE | thiG | XOO3816 | XOO3372 | Thiamine monophosphate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Nudix hydrolase family. | Thiamine biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.918 |
| ThiS | ThiE | XOO3371 | XOO3816 | Sulfur transfer protein involved in thiamine biosynthesis; With ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate. | Thiamine monophosphate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Nudix hydrolase family. | 0.799 |
| ThiS | dadA | XOO3371 | XOO0693 | Sulfur transfer protein involved in thiamine biosynthesis; With ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate. | D-amino acid dehydrogenase subunit; Oxidative deamination of D-amino acids. | 0.409 |
| ThiS | moeB-2 | XOO3371 | XOO2514 | Sulfur transfer protein involved in thiamine biosynthesis; With ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate. | Molybdopterin biosynthesis protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.956 |
| ThiS | thiC | XOO3371 | XOO0947 | Sulfur transfer protein involved in thiamine biosynthesis; With ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate. | Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.861 |
| ThiS | thiD | XOO3371 | XOO2928 | Sulfur transfer protein involved in thiamine biosynthesis; With ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate. | Phosphomethylpyrimidine kinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.804 |
| ThiS | thiE | XOO3371 | XOO1123 | Sulfur transfer protein involved in thiamine biosynthesis; With ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate. | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.821 |
| ThiS | thiG | XOO3371 | XOO3372 | Sulfur transfer protein involved in thiamine biosynthesis; With ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate. | Thiamine biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.998 |
| dadA | ThiS | XOO0693 | XOO3371 | D-amino acid dehydrogenase subunit; Oxidative deamination of D-amino acids. | Sulfur transfer protein involved in thiamine biosynthesis; With ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate. | 0.409 |
| dadA | thiG | XOO0693 | XOO3372 | D-amino acid dehydrogenase subunit; Oxidative deamination of D-amino acids. | Thiamine biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.778 |
| dxs | ThiE | XOO2017 | XOO3816 | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Thiamine monophosphate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Nudix hydrolase family. | 0.416 |
| dxs | thiG | XOO2017 | XOO3372 | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Thiamine biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.933 |
| micA | thiG | XOO3373 | XOO3372 | DNA mismatch repair protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | Thiamine biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.621 |
| moaD | moeB-2 | XOO1062 | XOO2514 | Molybdopterin-converting factor chain 1; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Molybdopterin biosynthesis protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.903 |