| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AdhC | CumB-2 | XOO3867 | XOO3720 | Zn-dependent alcohol dehydrogenases, class III; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Cytosine/adenosine deaminases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.420 |
| CumB-2 | AdhC | XOO3720 | XOO3867 | Cytosine/adenosine deaminases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Zn-dependent alcohol dehydrogenases, class III; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.420 |
| CumB-2 | XOO0570 | XOO3720 | XOO0570 | Cytosine/adenosine deaminases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.447 |
| CumB-2 | birA | XOO3720 | XOO0428 | Cytosine/adenosine deaminases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Biotin acetyl-CoA-carboxylase synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.809 |
| CumB-2 | guaA | XOO3720 | XOO2195 | Cytosine/adenosine deaminases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | 0.481 |
| CumB-2 | hisI | XOO3720 | XOO2262 | Cytosine/adenosine deaminases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase bifunctional enzyme; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the N-terminal section; belongs to the PRA-CH family. | 0.840 |
| CumB-2 | metS | XOO3720 | XOO1924 | Cytosine/adenosine deaminases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.459 |
| CumB-2 | polA | XOO3720 | XOO4240 | Cytosine/adenosine deaminases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.433 |
| CumB-2 | rlmM | XOO3720 | XOO3721 | Cytosine/adenosine deaminases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.858 |
| XOO0570 | CumB-2 | XOO0570 | XOO3720 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Cytosine/adenosine deaminases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.447 |
| birA | CumB-2 | XOO0428 | XOO3720 | Biotin acetyl-CoA-carboxylase synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Cytosine/adenosine deaminases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.809 |
| birA | guaA | XOO0428 | XOO2195 | Biotin acetyl-CoA-carboxylase synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | 0.698 |
| birA | metS | XOO0428 | XOO1924 | Biotin acetyl-CoA-carboxylase synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.669 |
| guaA | CumB-2 | XOO2195 | XOO3720 | Glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | Cytosine/adenosine deaminases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.481 |
| guaA | birA | XOO2195 | XOO0428 | Glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | Biotin acetyl-CoA-carboxylase synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.698 |
| guaA | hisI | XOO2195 | XOO2262 | Glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase bifunctional enzyme; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the N-terminal section; belongs to the PRA-CH family. | 0.459 |
| guaA | metS | XOO2195 | XOO1924 | Glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.853 |
| guaA | polA | XOO2195 | XOO4240 | Glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.708 |
| hisI | CumB-2 | XOO2262 | XOO3720 | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase bifunctional enzyme; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the N-terminal section; belongs to the PRA-CH family. | Cytosine/adenosine deaminases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.840 |
| hisI | guaA | XOO2262 | XOO2195 | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase bifunctional enzyme; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the N-terminal section; belongs to the PRA-CH family. | Glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | 0.459 |