| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| TDO2 | XOO4071 | XOO4075 | XOO4071 | Tryptophan 2,3-dioxygenase (vermilion); Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 4-hydroxyphenylpyruvate dioxygenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.591 |
| TDO2 | glbN | XOO4075 | XOO3240 | Tryptophan 2,3-dioxygenase (vermilion); Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Cyanoglobin; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.455 |
| TDO2 | iorA | XOO4075 | XOO4505 | Tryptophan 2,3-dioxygenase (vermilion); Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Indolepyruvate ferredoxin oxidoreductase chain alpha; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.476 |
| TDO2 | kynU | XOO4075 | XOO2428 | Tryptophan 2,3-dioxygenase (vermilion); Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.992 |
| TDO2 | nucH | XOO4075 | XOO4076 | Tryptophan 2,3-dioxygenase (vermilion); Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Nuclease; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.576 |
| TDO2 | pdhA | XOO4075 | XOO4077 | Tryptophan 2,3-dioxygenase (vermilion); Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Pyruvate dehydrogenase E1 alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.574 |
| TDO2 | pdhB-3 | XOO4075 | XOO4078 | Tryptophan 2,3-dioxygenase (vermilion); Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Pyruvate dehydrogenase E1 beta subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.524 |
| TDO2 | trpA | XOO4075 | XOO3251 | Tryptophan 2,3-dioxygenase (vermilion); Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.809 |
| TDO2 | trpB | XOO4075 | XOO3252 | Tryptophan 2,3-dioxygenase (vermilion); Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.800 |
| TDO2 | ybdL | XOO4075 | XOO2156 | Tryptophan 2,3-dioxygenase (vermilion); Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Succinyldiaminopimelate transaminase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.538 |
| XOO4071 | TDO2 | XOO4071 | XOO4075 | 4-hydroxyphenylpyruvate dioxygenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Tryptophan 2,3-dioxygenase (vermilion); Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.591 |
| glbN | TDO2 | XOO3240 | XOO4075 | Cyanoglobin; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Tryptophan 2,3-dioxygenase (vermilion); Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.455 |
| iorA | TDO2 | XOO4505 | XOO4075 | Indolepyruvate ferredoxin oxidoreductase chain alpha; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Tryptophan 2,3-dioxygenase (vermilion); Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.476 |
| iorA | trpA | XOO4505 | XOO3251 | Indolepyruvate ferredoxin oxidoreductase chain alpha; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.402 |
| iorA | ybdL | XOO4505 | XOO2156 | Indolepyruvate ferredoxin oxidoreductase chain alpha; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Succinyldiaminopimelate transaminase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.463 |
| kynU | TDO2 | XOO2428 | XOO4075 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | Tryptophan 2,3-dioxygenase (vermilion); Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.992 |
| kynU | trpA | XOO2428 | XOO3251 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.731 |
| kynU | ybdL | XOO2428 | XOO2156 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | Succinyldiaminopimelate transaminase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.568 |
| nucH | TDO2 | XOO4076 | XOO4075 | Nuclease; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Tryptophan 2,3-dioxygenase (vermilion); Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.576 |
| nucH | pdhA | XOO4076 | XOO4077 | Nuclease; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Pyruvate dehydrogenase E1 alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.572 |