| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HemX | HipB | XOO4087 | XOO0550 | Hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | PbsX family transcriptional regulator; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.760 |
| HemX | XOO0007 | XOO4087 | XOO0007 | Hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Putative Zn-dependent protease, contains TPR repeats; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.776 |
| HemX | XOO1138 | XOO4087 | XOO1138 | Hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.757 |
| HemX | ampE | XOO4087 | XOO0528 | Hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Transmembrane protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.754 |
| HemX | cysG | XOO4087 | XOO3102 | Hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Siroheme synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.909 |
| HemX | cysG-2 | XOO4087 | XOO3408 | Hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.909 |
| HemX | hemD | XOO4087 | XOO4088 | Hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.978 |
| HemX | hemE | XOO4087 | XOO1242 | Hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.906 |
| HemX | hemY | XOO4087 | XOO4086 | Hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Porphyrin biosynthesis protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.963 |
| HemX | uptE | XOO4087 | XOO0775 | Hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Outer membrane protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.763 |
| HipB | HemX | XOO0550 | XOO4087 | PbsX family transcriptional regulator; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.760 |
| HipB | XOO1138 | XOO0550 | XOO1138 | PbsX family transcriptional regulator; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.665 |
| HipB | ampE | XOO0550 | XOO0528 | PbsX family transcriptional regulator; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Transmembrane protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.684 |
| HipB | hemY | XOO0550 | XOO4086 | PbsX family transcriptional regulator; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Porphyrin biosynthesis protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.468 |
| HipB | uptE | XOO0550 | XOO0775 | PbsX family transcriptional regulator; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Outer membrane protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.741 |
| XOO0007 | HemX | XOO0007 | XOO4087 | Putative Zn-dependent protease, contains TPR repeats; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.776 |
| XOO0007 | uptE | XOO0007 | XOO0775 | Putative Zn-dependent protease, contains TPR repeats; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Outer membrane protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.736 |
| XOO1138 | HemX | XOO1138 | XOO4087 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.757 |
| XOO1138 | HipB | XOO1138 | XOO0550 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | PbsX family transcriptional regulator; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.665 |
| XOO1138 | ampE | XOO1138 | XOO0528 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Transmembrane protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.761 |