| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AmpD-2 | DdpX | XOO4100 | XOO4099 | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | D-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | 0.571 |
| AmpD-2 | Spr-3 | XOO4100 | XOO4101 | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Cell wall-associated hydrolases (invasion-associated proteins); Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.628 |
| AmpD-2 | XOO4098 | XOO4100 | XOO4098 | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.538 |
| AmpD-2 | ampG | XOO4100 | XOO0510 | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Signal transducer; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.828 |
| AmpD-2 | anmK | XOO4100 | XOO0512 | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.898 |
| AmpD-2 | ftsI | XOO4100 | XOO3831 | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.528 |
| AmpD-2 | mpl | XOO4100 | XOO0964 | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | UDP-N-acetylmuramate-L-alanine ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.525 |
| AmpD-2 | mrsA | XOO4100 | XOO3249 | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Phosphohexose mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.582 |
| AmpD-2 | nagZ | XOO4100 | XOO1867 | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | N-acetyl-beta-glucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.884 |
| AmpD-2 | tcbD | XOO4100 | XOO4102 | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Chloromuconate cycloisomerase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.601 |
| DdpX | AmpD-2 | XOO4099 | XOO4100 | D-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.571 |
| DdpX | Spr-3 | XOO4099 | XOO4101 | D-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | Cell wall-associated hydrolases (invasion-associated proteins); Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.508 |
| DdpX | XOO4098 | XOO4099 | XOO4098 | D-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.773 |
| DdpX | nagZ | XOO4099 | XOO1867 | D-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | N-acetyl-beta-glucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.419 |
| DdpX | tcbD | XOO4099 | XOO4102 | D-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | Chloromuconate cycloisomerase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.487 |
| Spr-3 | AmpD-2 | XOO4101 | XOO4100 | Cell wall-associated hydrolases (invasion-associated proteins); Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.628 |
| Spr-3 | DdpX | XOO4101 | XOO4099 | Cell wall-associated hydrolases (invasion-associated proteins); Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | D-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. | 0.508 |
| Spr-3 | XOO4098 | XOO4101 | XOO4098 | Cell wall-associated hydrolases (invasion-associated proteins); Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.509 |
| Spr-3 | tcbD | XOO4101 | XOO4102 | Cell wall-associated hydrolases (invasion-associated proteins); Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Chloromuconate cycloisomerase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.925 |
| XOO4098 | AmpD-2 | XOO4098 | XOO4100 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.538 |