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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpDAnthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (376 aa)    
Predicted Functional Partners:
trpE
Anthranilate synthase component I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
 0.999
trpE-2
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
 0.999
trpC
Indole-3-glycerol phosphate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the TrpC family.
  
 0.999
trpG
Anthranilate synthase component II; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
 0.999
trpF
N-(5'-phosphoribosyl) anthranilate isomerase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the TrpF family.
 
 
 0.998
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
  
 0.996
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.989
SerB-2
Phosphoserine phosphatase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
     
 0.841
trpS
tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.830
hisI
phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase bifunctional enzyme; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.743
Your Current Organism:
Xanthomonas oryzae
NCBI taxonomy Id: 291331
Other names: X. oryzae pv. oryzae KACC 10331, Xanthomonas oryzae pv. oryzae KACC 10331, Xanthomonas oryzae pv. oryzae str. KACC 10331, Xanthomonas oryzae pv. oryzae strain KACC 10331
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