| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NrdG | exsB | XOO1671 | XOO1679 | Organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | Transcriptional regulator; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.998 |
| NrdG | queF | XOO1671 | XOO4185 | Organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.908 |
| NrdG | queH | XOO1671 | XOO4337 | Organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | Conserved hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). | 0.415 |
| XOO4334 | metE | XOO4334 | XOO4333 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.940 |
| XOO4334 | metR | XOO4334 | XOO4336 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Transcriptional regulator metE/metH family; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the LysR transcriptional regulatory family. | 0.612 |
| XOO4334 | queH | XOO4334 | XOO4337 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). | 0.467 |
| XOO4334 | sflA | XOO4334 | XOO4335 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | NADH-dependent FMN reductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.812 |
| exsB | NrdG | XOO1679 | XOO1671 | Transcriptional regulator; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.998 |
| exsB | queA | XOO1679 | XOO2485 | Transcriptional regulator; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.524 |
| exsB | queF | XOO1679 | XOO4185 | Transcriptional regulator; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.990 |
| exsB | queH | XOO1679 | XOO4337 | Transcriptional regulator; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Conserved hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). | 0.412 |
| metE | XOO4334 | XOO4333 | XOO4334 | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.940 |
| metE | metF-2 | XOO4333 | XOO4338 | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 5,10-methylenetetrahydrofolate reductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the methylenetetrahydrofolate reductase family. | 0.797 |
| metE | metR | XOO4333 | XOO4336 | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Transcriptional regulator metE/metH family; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the LysR transcriptional regulatory family. | 0.784 |
| metE | queH | XOO4333 | XOO4337 | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). | 0.475 |
| metE | sflA | XOO4333 | XOO4335 | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | NADH-dependent FMN reductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.728 |
| metF-2 | metE | XOO4338 | XOO4333 | 5,10-methylenetetrahydrofolate reductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the methylenetetrahydrofolate reductase family. | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.797 |
| metF-2 | metR | XOO4338 | XOO4336 | 5,10-methylenetetrahydrofolate reductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the methylenetetrahydrofolate reductase family. | Transcriptional regulator metE/metH family; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the LysR transcriptional regulatory family. | 0.452 |
| metF-2 | queH | XOO4338 | XOO4337 | 5,10-methylenetetrahydrofolate reductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the methylenetetrahydrofolate reductase family. | Conserved hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). | 0.465 |
| metR | XOO4334 | XOO4336 | XOO4334 | Transcriptional regulator metE/metH family; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the LysR transcriptional regulatory family. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.612 |