close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MhpD-22-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway); Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (285 aa)    
Predicted Functional Partners:
ucpA
Oxidoreductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
  0.973
XOO4538
Predicted metal-dependent hydrolase of the TIM-barrel fold; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
     0.791
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
  
  
 0.613
Tas-4
Oxidoreductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
    0.547
XOO0340
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
     0.481
mphE
4-hydroxy-2-oxovalerate aldolase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the HpcH/HpaI aldolase family.
  
  
 0.456
PutA-2
NAD-dependent aldehyde dehydrogenases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
 
 0.426
kdgR
Transcriptional regulator; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
     0.406
badH
Aldehyde dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 
 0.403
Your Current Organism:
Xanthomonas oryzae
NCBI taxonomy Id: 291331
Other names: X. oryzae pv. oryzae KACC 10331, Xanthomonas oryzae pv. oryzae KACC 10331, Xanthomonas oryzae pv. oryzae str. KACC 10331, Xanthomonas oryzae pv. oryzae strain KACC 10331
Server load: medium (48%) [HD]