| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EntD | XOO4573 | XOO3083 | XOO4573 | Phosphopantetheinyl transferase component of siderophore synthetase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the P-Pant transferase superfamily. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.449 |
| Hlx | XOO4573 | XOO4574 | XOO4573 | Putative hemolysin; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.466 |
| XOO4527 | XOO4573 | XOO4527 | XOO4573 | Oxidoreductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.466 |
| XOO4573 | EntD | XOO4573 | XOO3083 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | Phosphopantetheinyl transferase component of siderophore synthetase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the P-Pant transferase superfamily. | 0.449 |
| XOO4573 | Hlx | XOO4573 | XOO4574 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | Putative hemolysin; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.466 |
| XOO4573 | XOO4527 | XOO4573 | XOO4527 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | Oxidoreductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.466 |
| XOO4573 | ada | XOO4573 | XOO1539 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | DNA methylation and regulatory protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.487 |
| XOO4573 | maeB | XOO4573 | XOO1118 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | NADP-dependent malic enzyme; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.467 |
| XOO4573 | mutL | XOO4573 | XOO2732 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.575 |
| XOO4573 | nadE | XOO4573 | XOO1595 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.461 |
| XOO4573 | nnrE | XOO4573 | XOO2735 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | Predicted sugar kinase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrE/AIBP family. | 0.433 |
| XOO4573 | ogt | XOO4573 | XOO1538 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 6-O-methylguanine-DNA methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.455 |
| XOO4573 | yhdG-3 | XOO4573 | XOO4572 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | Amino acid transporter; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.540 |
| ada | XOO4573 | XOO1539 | XOO4573 | DNA methylation and regulatory protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.487 |
| ada | ogt | XOO1539 | XOO1538 | DNA methylation and regulatory protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 6-O-methylguanine-DNA methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.972 |
| maeB | XOO4573 | XOO1118 | XOO4573 | NADP-dependent malic enzyme; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.467 |
| mutL | XOO4573 | XOO2732 | XOO4573 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.575 |
| mutL | nnrE | XOO2732 | XOO2735 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Predicted sugar kinase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrE/AIBP family. | 0.693 |
| nadE | XOO4573 | XOO1595 | XOO4573 | NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.461 |
| nadE | nnrE | XOO1595 | XOO2735 | NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Predicted sugar kinase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrE/AIBP family. | 0.496 |