STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIAESASA domain-containing protein. (536 aa)    
Predicted Functional Partners:
MAN2B2
Alpha-mannosidase.
    
 
 0.589
CD22
Uncharacterized protein.
      
 0.567
CASD1
CAS1 domain containing 1.
      
 0.567
ST3GAL2
Uncharacterized protein; Belongs to the glycosyltransferase 29 family.
      
 0.554
ST8SIA4
Uncharacterized protein; Belongs to the glycosyltransferase 29 family.
      
 0.549
URB1
Uncharacterized protein.
      
 0.547
MAN2B1
Alpha-mannosidase.
    
 
 0.526
BMT2
S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]
      
 0.505
LOC114031485
Uncharacterized protein.
      
 0.456
ENSVURP00010024462
annotation not available
      
 0.456
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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