STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB1Uncharacterized protein. (927 aa)    
Predicted Functional Partners:
E2F1
E2F transcription factor 1.
   
 0.999
CDK4
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.997
E2F2
E2F transcription factor 2.
   
 0.996
CDK2
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.996
CCND1
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
    
 0.995
E2F3
E2F_TDP domain-containing protein.
   
 0.994
E2F4
E2F_TDP domain-containing protein.
   
 0.994
CDK6
Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.994
CCNE1
Cyclin E1; Belongs to the cyclin family.
   
 0.993
HDAC2
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 0.993
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.