node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
deoD | punA | ERS852428_03830 | ERS852428_03416 | Putative purine nucleoside phosphorylase/uridine phosphorylase family protein. | Putative purine nucleoside phosphorylase I; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.833 |
deoD | surE | ERS852428_03830 | ERS852428_00755 | Putative purine nucleoside phosphorylase/uridine phosphorylase family protein. | 5'-nucleotidase /3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.796 |
deoD | udk_1 | ERS852428_03830 | ERS852428_01077 | Putative purine nucleoside phosphorylase/uridine phosphorylase family protein. | Putative phosphoribulose/uridine kinase. | 0.820 |
deoD | udk_2 | ERS852428_03830 | ERS852428_03695 | Putative purine nucleoside phosphorylase/uridine phosphorylase family protein. | Uridine kinase. | 0.820 |
deoD | upp | ERS852428_03830 | ERS852428_01127 | Putative purine nucleoside phosphorylase/uridine phosphorylase family protein. | Uracil phosphoribosyltransferase. | 0.855 |
deoD | yfkN_1 | ERS852428_03830 | ERS852428_00564 | Putative purine nucleoside phosphorylase/uridine phosphorylase family protein. | Metallophosphoesterase. | 0.792 |
glyA | guaA | ERS852428_02586 | ERS852428_03228 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.797 |
glyA | upp | ERS852428_02586 | ERS852428_01127 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Uracil phosphoribosyltransferase. | 0.781 |
guaA | glyA | ERS852428_03228 | ERS852428_02586 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.797 |
guaA | punA | ERS852428_03228 | ERS852428_03416 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Putative purine nucleoside phosphorylase I; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.602 |
guaA | pyrF | ERS852428_03228 | ERS852428_00931 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Putative orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.628 |
guaA | pyrH | ERS852428_03228 | ERS852428_00696 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Putative uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.795 |
guaA | surE | ERS852428_03228 | ERS852428_00755 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 5'-nucleotidase /3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.916 |
guaA | upp | ERS852428_03228 | ERS852428_01127 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Uracil phosphoribosyltransferase. | 0.942 |
guaA | yfkN_1 | ERS852428_03228 | ERS852428_00564 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Metallophosphoesterase. | 0.818 |
punA | deoD | ERS852428_03416 | ERS852428_03830 | Putative purine nucleoside phosphorylase I; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Putative purine nucleoside phosphorylase/uridine phosphorylase family protein. | 0.833 |
punA | guaA | ERS852428_03416 | ERS852428_03228 | Putative purine nucleoside phosphorylase I; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.602 |
punA | surE | ERS852428_03416 | ERS852428_00755 | Putative purine nucleoside phosphorylase I; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 5'-nucleotidase /3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.796 |
punA | udk_1 | ERS852428_03416 | ERS852428_01077 | Putative purine nucleoside phosphorylase I; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Putative phosphoribulose/uridine kinase. | 0.529 |
punA | udk_2 | ERS852428_03416 | ERS852428_03695 | Putative purine nucleoside phosphorylase I; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Uridine kinase. | 0.529 |