node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CUN10805.1 | flr_2 | ERS852428_02587 | ERS852428_02588 | Uncharacterised protein. | Conserved protein/domain typically associated with flavoprotein oxygenases%2C DIM6/NTAB family. | 0.704 |
CUN10805.1 | glyA | ERS852428_02587 | ERS852428_02586 | Uncharacterised protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.685 |
CUN10805.1 | pyrB | ERS852428_02587 | ERS852428_02590 | Uncharacterised protein. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.527 |
CUN10805.1 | pyrI | ERS852428_02587 | ERS852428_02589 | Uncharacterised protein. | Aspartate carbamoyltransferase; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.585 |
flr_1 | flr_2 | ERS852428_01533 | ERS852428_02588 | Putative flavoredoxin. | Conserved protein/domain typically associated with flavoprotein oxygenases%2C DIM6/NTAB family. | 0.403 |
flr_1 | pyrK | ERS852428_01533 | ERS852428_02150 | Putative flavoredoxin. | Putative dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.400 |
flr_2 | CUN10805.1 | ERS852428_02588 | ERS852428_02587 | Conserved protein/domain typically associated with flavoprotein oxygenases%2C DIM6/NTAB family. | Uncharacterised protein. | 0.704 |
flr_2 | flr_1 | ERS852428_02588 | ERS852428_01533 | Conserved protein/domain typically associated with flavoprotein oxygenases%2C DIM6/NTAB family. | Putative flavoredoxin. | 0.403 |
flr_2 | glyA | ERS852428_02588 | ERS852428_02586 | Conserved protein/domain typically associated with flavoprotein oxygenases%2C DIM6/NTAB family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.600 |
flr_2 | pyrB | ERS852428_02588 | ERS852428_02590 | Conserved protein/domain typically associated with flavoprotein oxygenases%2C DIM6/NTAB family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.578 |
flr_2 | pyrI | ERS852428_02588 | ERS852428_02589 | Conserved protein/domain typically associated with flavoprotein oxygenases%2C DIM6/NTAB family. | Aspartate carbamoyltransferase; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.712 |
flr_2 | pyrK | ERS852428_02588 | ERS852428_02150 | Conserved protein/domain typically associated with flavoprotein oxygenases%2C DIM6/NTAB family. | Putative dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.400 |
glyA | CUN10805.1 | ERS852428_02586 | ERS852428_02587 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Uncharacterised protein. | 0.685 |
glyA | flr_2 | ERS852428_02586 | ERS852428_02588 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Conserved protein/domain typically associated with flavoprotein oxygenases%2C DIM6/NTAB family. | 0.600 |
glyA | pyrB | ERS852428_02586 | ERS852428_02590 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.593 |
glyA | pyrI | ERS852428_02586 | ERS852428_02589 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aspartate carbamoyltransferase; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.529 |
pyrB | CUN10805.1 | ERS852428_02590 | ERS852428_02587 | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Uncharacterised protein. | 0.527 |
pyrB | flr_2 | ERS852428_02590 | ERS852428_02588 | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Conserved protein/domain typically associated with flavoprotein oxygenases%2C DIM6/NTAB family. | 0.578 |
pyrB | glyA | ERS852428_02590 | ERS852428_02586 | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.593 |
pyrB | pyrI | ERS852428_02590 | ERS852428_02589 | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Aspartate carbamoyltransferase; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.999 |