STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANCCAN_04022Guanylate cyclase. (1211 aa)    
Predicted Functional Partners:
ANCCAN_27741
Nucleoside diphosphate kinase.
    
 0.771
ANCCAN_02679
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.766
ANCCAN_02177
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.766
ANCCAN_29410
Immunoglobulin I-set domain protein.
     
 0.721
ANCCAN_28731
Immunoglobulin I-set domain protein.
     
 0.721
ANCCAN_27127
Fibronectin type III domain protein.
     
 0.721
ANCCAN_11498
Uncharacterized protein.
     
 0.721
ANCCAN_11506
Immunoglobulin I-set domain protein.
     
 0.721
ANCCAN_11505
Immunoglobulin I-set domain protein.
     
 0.721
ANCCAN_11508
Uncharacterized protein.
     
 0.721
Your Current Organism:
Ancylostoma caninum
NCBI taxonomy Id: 29170
Other names: A. caninum, dog hookworm
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