Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
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Fusion
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WL94_14860
annotation not available (131 aa)
Predicted Functional Partners:
WL94_14870
annotation not available
0.715
WI67_14555
annotation not available
0.529
WL94_35110
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1
node2
node1 accession
node2 accession
node1 annotation
node2 annotation
score
WI67_14555
WL94_14860
DM42_2352
DM42_2357
annotation not available
annotation not available
0.529
WL94_14860
WI67_14555
DM42_2357
DM42_2352
annotation not available
annotation not available
0.529
WL94_14860
WL94_14870
DM42_2357
DM42_2358
annotation not available
annotation not available
0.715
WL94_14860
WL94_35110
DM42_2357
DM42_1245
annotation not available
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
0.409
WL94_14870
WL94_14860
DM42_2358
DM42_2357
annotation not available
annotation not available
0.715
WL94_35110
WL94_14860
DM42_1245
DM42_2357
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
annotation not available
0.409
Network Stats
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Functional enrichments in your networkNote: some enrichments may be expected here (why?) explain columns
Enrichment analysis is still ongoing, please wait ...
Statistical background
For the above enrichment analysis, the following statistical background is assumed: