STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rfaFheptsyl_trn_II: lipopolysaccharide heptosyltransferase II (345 aa)    
Predicted Functional Partners:
waaC
heptsyl_trn_I: lipopolysaccharide heptosyltransferase I
 0.995
RfaC
heptsyl_trn_I: lipopolysaccharide heptosyltransferase I
0.951
rfaD
Adp-l-glycero-d-manno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose
 
  
 0.947
rfaE1
D-glycero-beta-D-manno-heptose-7-phosphate kinase; Domain I; rfaE_dom_I: bifunctional protein RfaE, domain I
 
 0.943
DM42_2752
annotation not available
 
0.918
DM42_932
3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A
 
 
 0.910
gmhB
D-glycero-d-manno-heptose 1,7-bisphosphate phosphatase; D,D-heptose 1,7-bisphosphate phosphatase; HAD-SF-IIIA: HAD hydrolase, family IIIA domain protein
 
 
 0.872
rfaE2
D-glycero-beta-d-manno-heptose 1-phosphate adenylyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose
 
  
 0.850
DM42_1538
annotation not available
 
 
 
 0.778
DM42_7140
D-glycero-d-manno-heptose 1,7-bisphosphate phosphatase; HAD-SF-IA-v1: HAD hydrolase, IA, variant 1 family protein
   
 0.741
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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