STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurence
Coexpression
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[Homology]
Score
clsCardiolipin synthase a/b; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (479 aa)    
Predicted Functional Partners:
DM42_1213
Phosphatidylglycerophosphatase a family protein; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
  
 0.921
DM42_2894
HAD family hydrolase; HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein
    
 0.900
clsB
Phospholipase d family protein; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
  
  
0.883
DM42_1809
PC_PLC: phospholipase C, phosphocholine-specific
     
 0.657
DM42_3615
annotation not available
     
 0.657
DM42_4744
PC_PLC: phospholipase C, phosphocholine-specific
     
 0.657
DM42_5264
PC_PLC: phospholipase C, phosphocholine-specific
     
 0.657
DM42_5553
PC_PLC: phospholipase C, phosphocholine-specific
     
 0.657
DM42_556
PC_PLC: phospholipase C, phosphocholine-specific
     
 0.657
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
     
 0.589
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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