nnrD protein (Burkholderia cepacia) - STRING interaction network

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nnrD

Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family (514 aa)

Predicted Functional Partners:

WI67_18165

0.999

queG

0.975

ruvC

0.922

WI67_13815

0.880

WL94_36035

0.875

WL94_04580

0.855

DM42_576

0.855

DM42_5206

0.855

WL94_10945

0.855

hflX

0.838

Your Current Organism:

Burkholderia cepacia

NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DM42_5206	nnrD	DM42_5206	DM42_3184	annotation not available	Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family	0.855
DM42_576	WL94_04580	DM42_576	DM42_6142	annotation not available	annotation not available	0.845
DM42_576	nnrD	DM42_576	DM42_3184	annotation not available	Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family	0.855
DM42_576	queG	DM42_576	DM42_2507	annotation not available	Epoxyqueuosine reductase; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family	0.535
DM42_576	ruvC	DM42_576	DM42_1152	annotation not available	Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5’-terminal phosphate and a 3’-terminal hydroxyl group	0.541
WI67_13815	hflX	DM42_2506	DM42_3294	tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; T6A_YjeE- tRNA threonylcarbamoyl adenosine modification protein YjeE	GTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	0.405
WI67_13815	nnrD	DM42_2506	DM42_3184	tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; T6A_YjeE- tRNA threonylcarbamoyl adenosine modification protein YjeE	Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family	0.880
WI67_13815	queG	DM42_2506	DM42_2507	tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; T6A_YjeE- tRNA threonylcarbamoyl adenosine modification protein YjeE	Epoxyqueuosine reductase; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family	0.800
WI67_18165	WL94_36035	DM42_4793	DM42_5826	annotation not available	annotation not available	0.767
WI67_18165	nnrD	DM42_4793	DM42_3184	annotation not available	Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family	0.999
WL94_04580	DM42_576	DM42_6142	DM42_576	annotation not available	annotation not available	0.845
WL94_04580	nnrD	DM42_6142	DM42_3184	annotation not available	Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family	0.855
WL94_10945	nnrD	DM42_4459	DM42_3184	annotation not available	Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family	0.855
WL94_36035	WI67_18165	DM42_5826	DM42_4793	annotation not available	annotation not available	0.767
WL94_36035	nnrD	DM42_5826	DM42_3184	annotation not available	Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family	0.875
hflX	WI67_13815	DM42_3294	DM42_2506	GTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; T6A_YjeE- tRNA threonylcarbamoyl adenosine modification protein YjeE	0.405
hflX	nnrD	DM42_3294	DM42_3184	GTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family	0.838
nnrD	DM42_5206	DM42_3184	DM42_5206	Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family	annotation not available	0.855
nnrD	DM42_576	DM42_3184	DM42_576	Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family	annotation not available	0.855
nnrD	WI67_13815	DM42_3184	DM42_2506	Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family	tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; T6A_YjeE- tRNA threonylcarbamoyl adenosine modification protein YjeE	0.880

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