STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOI86783.1
Alkene reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
Predicted Functional Partners:
dkgB
Catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; Derived by automated computational analysis using gene prediction method: Protein Homology.
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1
node2
node1 accession
node2 accession
node1 annotation
node2 annotation
score
AOI86783.1
dkgB
WI67_31120
WI67_31115
Alkene reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
Catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; Derived by automated computational analysis using gene prediction method: Protein Homology.
0.648
dkgB
AOI86783.1
WI67_31115
WI67_31120
Catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; Derived by automated computational analysis using gene prediction method: Protein Homology.
Alkene reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
0.648
Network Stats
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Functional enrichments in your networkNote: some enrichments may be expected here (why?) disable highlightexplain columns
Enrichment analysis is still ongoing, please wait ...
Statistical background
For the above enrichment analysis, the following statistical background is assumed: