Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
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Fusion
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dan
annotation not available (503 aa)
Predicted Functional Partners:
DM42_5731
annotation not available
0.845
DM42_5730
annotation not available
0.821
WL94_14725
annotation not available
0.799
WI67_14660
annotation not available
0.512
DM42_5733
annotation not available
0.493
WL94_14730
annotation not available
0.491
WL94_39175
annotation not available
0.475
WI67_02320
Haloacid dehalogenase; HAD-SF-IA-v3: HAD hydrolase, IA, variant 3 family protein
0.470
WI67_15610
Carbonic anhydrase; Reversible hydration of carbon dioxide
0.470
WL94_24180
Carbonic anhydrase; Reversible hydration of carbon dioxide