node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AOI86469.1 | AceA | WI67_29305 | WI67_11115 | Isocitrate lyase; Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
AOI86469.1 | acnA | WI67_29305 | WI67_21810 | Isocitrate lyase; Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.915 |
AOI86469.1 | acnB | WI67_29305 | WI67_27040 | Isocitrate lyase; Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aconitate hydratase B; Catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family. | 0.924 |
AceA | AOI86469.1 | WI67_11115 | WI67_29305 | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isocitrate lyase; Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
AceA | acnA | WI67_11115 | WI67_21810 | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.915 |
AceA | acnB | WI67_11115 | WI67_27040 | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aconitate hydratase B; Catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family. | 0.923 |
PrpF | acnA | WI67_31610 | WI67_21810 | 3-methylitaconate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.795 |
PrpF | acnB | WI67_31610 | WI67_27040 | 3-methylitaconate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aconitate hydratase B; Catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family. | 0.930 |
PrpF | prpB | WI67_31610 | WI67_31625 | 3-methylitaconate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.860 |
PrpF | prpD | WI67_31610 | WI67_21815 | 3-methylitaconate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-methylcitrate dehydratase; Functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.960 |
acnA | AOI86469.1 | WI67_21810 | WI67_29305 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Isocitrate lyase; Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.915 |
acnA | AceA | WI67_21810 | WI67_11115 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.915 |
acnA | PrpF | WI67_21810 | WI67_31610 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 3-methylitaconate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.795 |
acnA | acnB | WI67_21810 | WI67_27040 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Aconitate hydratase B; Catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family. | 0.951 |
acnA | gltA | WI67_21810 | WI67_21865 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.987 |
acnA | icd | WI67_21810 | WI67_13625 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.986 |
acnA | icd_2 | WI67_21810 | WI67_13620 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. | 0.928 |
acnA | mdh | WI67_21810 | WI67_21830 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.578 |
acnA | prpB | WI67_21810 | WI67_31625 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.426 |
acnA | prpD | WI67_21810 | WI67_21815 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 2-methylcitrate dehydratase; Functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.724 |