STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DmpG4-hydroxy-2-oxovalerate/4-hydroxy-2-oxohexanoate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds (343 aa)    
Predicted Functional Partners:
DM42_6344
Acetaldehyde/propanal dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds
 0.998
DmpE
2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase; catechol_dmpE: 2-oxopent-4-enoate hydratase
 
 
 0.995
DM42_4992
Acetaldehyde/propanal dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds
 0.993
dmpE
2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase; catechol_dmpE: 2-oxopent-4-enoate hydratase
 
 
 0.982
DM42_7210
annotation not available
 
 
 0.943
dmpG
4-hydroxy-2-oxovalerate/4-hydroxy-2-oxohexanoate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds
  
  
 
0.901
dmpH
2-oxo-3-hexenedioate decarboxylase; catechol_dmpH: 4-oxalocrotonate decarboxylase
 
  
 0.829
XylF
annotation not available
 
   
 0.820
DM42_6349
annotation not available
 
   
 0.757
DM42_4996
Catechol 2,3-dioxygenase; Catechol_2_3: catechol 2,3 dioxygenase
 
 
 0.737
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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