| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AOI81817.1 | AOI82247.1 | WI67_04835 | WI67_07160 | DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.760 |
| AOI81817.1 | dinG_2 | WI67_04835 | WI67_09565 | DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.944 |
| AOI81817.1 | dnaE | WI67_04835 | WI67_12565 | DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit alpha; Catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.740 |
| AOI81817.1 | dnaE2 | WI67_04835 | WI67_15110 | DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.740 |
| AOI81817.1 | dnaN | WI67_04835 | WI67_00010 | DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.838 |
| AOI81817.1 | dnaX | WI67_04835 | WI67_09730 | DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.823 |
| AOI81817.1 | mutM | WI67_04835 | WI67_14965 | DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.863 |
| AOI81817.1 | radA | WI67_04835 | WI67_11065 | DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.871 |
| AOI81817.1 | rep | WI67_04835 | WI67_00850 | DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. | 0.755 |
| AOI81817.1 | uvrB | WI67_04835 | WI67_12000 | DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.949 |
| AOI82247.1 | AOI81817.1 | WI67_07160 | WI67_04835 | DNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.760 |
| AOI82247.1 | dnaE | WI67_07160 | WI67_12565 | DNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit alpha; Catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.425 |
| AOI82247.1 | dnaN | WI67_07160 | WI67_00010 | DNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.779 |
| AOI82247.1 | radA | WI67_07160 | WI67_11065 | DNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.437 |
| AOI82247.1 | uvrB | WI67_07160 | WI67_12000 | DNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.785 |
| dinG_2 | AOI81817.1 | WI67_09565 | WI67_04835 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.944 |
| dinG_2 | dnaE | WI67_09565 | WI67_12565 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit alpha; Catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.469 |
| dinG_2 | dnaE2 | WI67_09565 | WI67_15110 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.442 |
| dinG_2 | dnaN | WI67_09565 | WI67_00010 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.740 |
| dinG_2 | mutM | WI67_09565 | WI67_14965 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.400 |