Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AOI81893.1Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)    
Predicted Functional Partners:
RpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.790
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.636
AmiC
Amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
      0.559
AOI83048.1
PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.523
fliM
Flagellar motor switch protein FliM; With FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.445
fliP
Flagellar biosynthesis protein flip; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
  
  
 0.427
AOI85250.1
Chemotaxis protein CheA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.427
fliN
Flagellar motor switch protein FliN; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.414
AOI81019.1
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
  
 0.414
AOI81130.1
Chemotaxis protein CheA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.405
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, Burkholderia sp. Bp7081, Burkholderia sp. Bp7091, Burkholderia sp. Bp7098, Burkholderia sp. Bp7108, Burkholderia sp. Bp7432, Burkholderia sp. LK29, Burkholderia sp. NCIM 5465, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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