Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
YihYHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)    
Predicted Functional Partners:
hemL
Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.741
AOI82258.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.652
WrbA
NAD(P)H-quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the WrbA family.
       0.605
gca
GDP-mannose 4,6 dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
      
 0.581
AOI82257.1
Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.544
AOI83001.1
SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.508
fliP
Flagellar biosynthesis protein flip; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
      
 0.477
AOI82256.1
Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.454
typA
GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.434
chaA
Ionic transporter y4hA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.407
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, Burkholderia sp. Bp7081, Burkholderia sp. Bp7091, Burkholderia sp. Bp7098, Burkholderia sp. Bp7108, Burkholderia sp. Bp7432, Burkholderia sp. LK29, Burkholderia sp. NCIM 5465, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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