Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AOI82413.1Multidrug transporter; MexX; AmrA; involved in resistance to antibiotics; periplasmic membrane fusion protein; functions along with MexY and OprM; part of an inducible system that appears to respond to interference with the cellular translation machinery; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)    
Predicted Functional Partners:
AOI82414.1
Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.993
AOI83491.1
Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.970
AOI86315.1
Acriflavine resistance protein B; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.969
AOI84124.1
Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.939
macB
Macrolide transporter; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.903
AOI85471.1
RND transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.877
AOI82583.1
Acriflavine resistance protein B; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.853
AOI87195.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.839
AOI86739.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.839
AOI83490.1
Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.826
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, Burkholderia sp. Bp7081, Burkholderia sp. Bp7091, Burkholderia sp. Bp7098, Burkholderia sp. Bp7108, Burkholderia sp. Bp7432, Burkholderia sp. LK29, Burkholderia sp. NCIM 5465, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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