STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gclGlyoxylate carboligase; Catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (591 aa)    
Predicted Functional Partners:
hyi
Hydroxypyruvate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the hyi family.
 
 
 0.994
garR_1
2-hydroxy-3-oxopropionate reductase; NADH-dependent; catalyzed the reversible formation of glycerate from tartronate semialdehyde; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.989
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
    
 0.940
AceA
Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.918
AceB
Malate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family.
    
 0.916
AOI86469.1
Isocitrate lyase; Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.908
glcF
Glycolate oxidase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.902
ghrB_2
D-glycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.902
GhrB
D-glycerate dehydrogenase; Catalyzes the formation of glycolate from glyoxylate and glycerate from hydroxypyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.902
glcF-2
Glycolate oxidase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.902
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, Burkholderia sp. Bp7081, Burkholderia sp. Bp7091, Burkholderia sp. Bp7098, Burkholderia sp. Bp7108, Burkholderia sp. Bp7432, Burkholderia sp. LK29, Burkholderia sp. NCIM 5465, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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