| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AOI82114.1 | AOI82665.1 | WI67_06440 | WI67_09540 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.916 |
| AOI82114.1 | AOI84209.1 | WI67_06440 | WI67_14830 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. | 0.916 |
| AOI82114.1 | AOI85235.1 | WI67_06440 | WI67_22485 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.904 |
| AOI82114.1 | AOI86381.1 | WI67_06440 | WI67_28815 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.923 |
| AOI82114.1 | AOI86871.1 | WI67_06440 | WI67_31620 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Citrate synthase/methylcitrate synthase; Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.927 |
| AOI82114.1 | AceB | WI67_06440 | WI67_11135 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. | 0.927 |
| AOI82114.1 | Acs | WI67_06440 | WI67_11910 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetyl-coenzyme A synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.918 |
| AOI82114.1 | glcB | WI67_06440 | WI67_32235 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.927 |
| AOI82114.1 | gltA | WI67_06440 | WI67_21865 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.927 |
| AOI82114.1 | scpC | WI67_06440 | WI67_22850 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.927 |
| AOI82665.1 | AOI82114.1 | WI67_09540 | WI67_06440 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.916 |
| AOI82665.1 | AOI84209.1 | WI67_09540 | WI67_14830 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. | 0.900 |
| AOI82665.1 | AOI85235.1 | WI67_09540 | WI67_22485 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.904 |
| AOI82665.1 | AOI86381.1 | WI67_09540 | WI67_28815 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.916 |
| AOI82665.1 | AOI86871.1 | WI67_09540 | WI67_31620 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | Citrate synthase/methylcitrate synthase; Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.931 |
| AOI82665.1 | AceB | WI67_09540 | WI67_11135 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. | 0.911 |
| AOI82665.1 | Acs | WI67_09540 | WI67_11910 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetyl-coenzyme A synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.916 |
| AOI82665.1 | glcB | WI67_09540 | WI67_32235 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.911 |
| AOI82665.1 | gltA | WI67_09540 | WI67_21865 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.931 |
| AOI82665.1 | scpC | WI67_09540 | WI67_22850 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.909 |
