STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
envZ_4Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)    
Predicted Functional Partners:
ompR
Part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.996
ompR-2
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.984
AOI82807.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.924
ompR_2
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.822
basR_6
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.814
phoB
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.809
rstA_1
XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.792
rstA_2
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.771
AOI83500.1
XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.768
basR_7
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.767
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, Burkholderia sp. Bp7081, Burkholderia sp. Bp7091, Burkholderia sp. Bp7098, Burkholderia sp. Bp7108, Burkholderia sp. Bp7432, Burkholderia sp. LK29, Burkholderia sp. NCIM 5465, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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