| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AOI83310.1 | AOI83311.1 | WI67_13100 | WI67_13105 | Heme biosynthesis protein HemY; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.982 |
| AOI83310.1 | hemC | WI67_13100 | WI67_13110 | Heme biosynthesis protein HemY; Derived by automated computational analysis using gene prediction method: Protein Homology. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.844 |
| AOI83311.1 | AOI83310.1 | WI67_13105 | WI67_13100 | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Heme biosynthesis protein HemY; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.982 |
| AOI83311.1 | AOI84130.1 | WI67_13105 | WI67_08255 | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.428 |
| AOI83311.1 | AOI87158.1 | WI67_13105 | WI67_25400 | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.428 |
| AOI83311.1 | cysG_2 | WI67_13105 | WI67_13335 | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. | 0.532 |
| AOI83311.1 | hemA_2 | WI67_13105 | WI67_02295 | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.693 |
| AOI83311.1 | hemB | WI67_13105 | WI67_01675 | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. | 0.895 |
| AOI83311.1 | hemC | WI67_13105 | WI67_13110 | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.996 |
| AOI83311.1 | hemE | WI67_13105 | WI67_00665 | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.536 |
| AOI83311.1 | hemL | WI67_13105 | WI67_04585 | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.525 |
| AOI84130.1 | AOI83311.1 | WI67_08255 | WI67_13105 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.428 |
| AOI84130.1 | AOI87158.1 | WI67_08255 | WI67_25400 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.543 |
| AOI84130.1 | CobM | WI67_08255 | WI67_08400 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Precorrin-4 C(11)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.680 |
| AOI84130.1 | hemA_2 | WI67_08255 | WI67_02295 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.778 |
| AOI84130.1 | hemB | WI67_08255 | WI67_01675 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. | 0.853 |
| AOI84130.1 | hemC | WI67_08255 | WI67_13110 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.985 |
| AOI84130.1 | hemL | WI67_08255 | WI67_04585 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.717 |
| AOI87158.1 | AOI83311.1 | WI67_25400 | WI67_13105 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.428 |
| AOI87158.1 | AOI84130.1 | WI67_25400 | WI67_08255 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.543 |