Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
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Experiments
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[Homology]
Score
AOI83936.1Cobalamin biosynthesis protein CobW; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)    
Predicted Functional Partners:
rpsN
30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
  
 
 0.539
rlmI
23S rRNA methyltransferase; SAM-dependent;catalyzes the methylation of cytosine at position 1962 of the 23S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.536
dksA
RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.
  
  
 0.528
AOI83482.1
Cation ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family.
  
  
 0.507
rpmB
50S ribosomal protein L28; Required for 70S ribosome assembly; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.477
AOI82458.1
Cobalamin biosynthesis protein CbiG; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.461
folE2_1
GTP cyclohydrolase FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate.
  
  
 0.455
folE2
GTP cyclohydrolase FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate.
  
  
 0.455
AOI83933.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.449
yocK
Conjugal transfer protein TraR; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.442
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, Burkholderia sp. Bp7081, Burkholderia sp. Bp7091, Burkholderia sp. Bp7098, Burkholderia sp. Bp7108, Burkholderia sp. Bp7432, Burkholderia sp. LK29, Burkholderia sp. NCIM 5465, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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