| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AOI86496.1 | AOI86499.1 | WI67_29465 | WI67_29480 | Drug:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | N-methylproline demethylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
| AOI86496.1 | AOI86571.1 | WI67_29465 | WI67_29900 | Drug:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sarcosine oxidase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.978 |
| AOI86496.1 | gcvP | WI67_29465 | WI67_00820 | Drug:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.912 |
| AOI86496.1 | glyA | WI67_29465 | WI67_03825 | Drug:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.909 |
| AOI86496.1 | glyA-2 | WI67_29465 | WI67_29495 | Drug:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.937 |
| AOI86496.1 | kbl | WI67_29465 | WI67_16915 | Drug:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-amino-3-ketobutyrate CoA ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.902 |
| AOI86496.1 | ltaE | WI67_29465 | WI67_31440 | Drug:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.902 |
| AOI86496.1 | soxB_2 | WI67_29465 | WI67_29910 | Drug:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.945 |
| AOI86499.1 | AOI86496.1 | WI67_29480 | WI67_29465 | N-methylproline demethylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Drug:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
| AOI86499.1 | AOI86571.1 | WI67_29480 | WI67_29900 | N-methylproline demethylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sarcosine oxidase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.966 |
| AOI86499.1 | gcvP | WI67_29480 | WI67_00820 | N-methylproline demethylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.934 |
| AOI86499.1 | glyA | WI67_29480 | WI67_03825 | N-methylproline demethylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.917 |
| AOI86499.1 | glyA-2 | WI67_29480 | WI67_29495 | N-methylproline demethylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.943 |
| AOI86499.1 | kbl | WI67_29480 | WI67_16915 | N-methylproline demethylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-amino-3-ketobutyrate CoA ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.904 |
| AOI86499.1 | ltaE | WI67_29480 | WI67_31440 | N-methylproline demethylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.903 |
| AOI86499.1 | soxB_2 | WI67_29480 | WI67_29910 | N-methylproline demethylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.955 |
| AOI86571.1 | AOI86496.1 | WI67_29900 | WI67_29465 | Sarcosine oxidase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Drug:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.978 |
| AOI86571.1 | AOI86499.1 | WI67_29900 | WI67_29480 | Sarcosine oxidase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | N-methylproline demethylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.966 |
| AOI86571.1 | gcvP | WI67_29900 | WI67_00820 | Sarcosine oxidase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.998 |
| AOI86571.1 | glyA | WI67_29900 | WI67_03825 | Sarcosine oxidase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.970 |
