Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AOI84898.1Histidine kinase; Member of a two-component regulatory system. (476 aa)    
Predicted Functional Partners:
copR_1
Response regulator in two-component regulatory system with CusS; regulates the copper efflux system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.996
AOI84593.1
Response regulator in two-component regulatory system with CusS; regulates the copper efflux system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.987
AOI85468.1
Response regulator in two-component regulatory system with CusS; regulates the copper efflux system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.985
AOI85467.1
Histidine kinase; Member of a two-component regulatory system.
  
  
 
0.924
AOI84592.1
Histidine kinase; Member of a two-component regulatory system.
  
  
 
0.914
AOI82368.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.893
AOI83500.1
XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.857
basR_1
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.854
basR_7
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.849
AOI83531.1
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.848
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, Burkholderia sp. Bp7081, Burkholderia sp. Bp7091, Burkholderia sp. Bp7098, Burkholderia sp. Bp7108, Burkholderia sp. Bp7432, Burkholderia sp. LK29, Burkholderia sp. NCIM 5465, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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