Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AOI85350.1Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)    
Predicted Functional Partners:
AOI85351.1
Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.977
gsiC
Glutathione ABC transporter permease; With GsiABD is involved in the transport of glutathione into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology.
    0.908
gsiD
Glutathione ABC transporter permease; With GsiABD is involved in the transport of glutathione into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.866
AOI85939.1
Mandelate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.818
AOI83609.1
Amino acid deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.815
AOI85347.1
Glutathione ABC transporter substrate-binding protein; With GsiACD is involved in the transport of glutathione into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.709
speH
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
      
 0.586
AOI85345.1
Isoaspartyl peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.491
ybbH_1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.475
glnE
Glutamine-synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...]
      
 0.460
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, Burkholderia sp. Bp7081, Burkholderia sp. Bp7091, Burkholderia sp. Bp7098, Burkholderia sp. Bp7108, Burkholderia sp. Bp7432, Burkholderia sp. LK29, Burkholderia sp. NCIM 5465, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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