STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOI85444.1Glycerophosphodiester phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)    
Predicted Functional Partners:
ugpQ
Glycerophosphoryl diester phosphodiesterase; Hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.918
AOI81089.1
Ethanolamine ammonia-lyase; With EutC catalyzes the formation of acetaldehyde and ammonia from ethanolamine; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
eutC
Ethanolamine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the EutC family.
     
  0.900
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
  
 0.857
gla
Aquaporin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MIP/aquaporin (TC 1.A.8) family.
 
 
 0.823
aqpZ
Aquaporin; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.798
AOI83556.1
Glycerol-3-phosphate dehydrogenase; In Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 0.763
cca
2', 3'-cyclic nucleotide 2'-phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
     
 0.575
AOI87070.1
5-oxoprolinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.543
acdS
Aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase family protein; Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source; Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
  
   
 0.485
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, Burkholderia sp. Bp7081, Burkholderia sp. Bp7091, Burkholderia sp. Bp7098, Burkholderia sp. Bp7108, Burkholderia sp. Bp7432, Burkholderia sp. LK29, Burkholderia sp. NCIM 5465, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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