Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
luxA_15,10-methylene tetrahydromethanopterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)    
Predicted Functional Partners:
nuoH
NADH:ubiquinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.
      
 0.717
AOI85729.1
Flavin reductase domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.608
AOI84714.1
Rhodanese; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.586
AOI86339.1
Rhodanese; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.586
AOI82136.1
Dipeptidyl aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.584
topB
DNA topoisomerase III; Decatenates replicating daughter chromosomes; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.583
AOI85731.1
Flavin-dependent monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.552
AOI82137.1
3-(3-hydroxyphenyl)propionate hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.520
AOI87083.1
MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.519
AOI83077.1
Polyketide cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.505
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, Burkholderia sp. Bp7081, Burkholderia sp. Bp7091, Burkholderia sp. Bp7098, Burkholderia sp. Bp7108, Burkholderia sp. Bp7432, Burkholderia sp. LK29, Burkholderia sp. NCIM 5465, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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