| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AOI83311.1 | AOI84130.1 | WI67_13105 | WI67_08255 | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.926 |
| AOI83311.1 | AOI87158.1 | WI67_13105 | WI67_25400 | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.926 |
| AOI83311.1 | CobI | WI67_13105 | WI67_08365 | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Precorrin-2 C(20)-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | 0.920 |
| AOI83311.1 | cysG_2 | WI67_13105 | WI67_13335 | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. | 0.940 |
| AOI83311.1 | hemA_2 | WI67_13105 | WI67_02295 | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.675 |
| AOI83311.1 | hemB | WI67_13105 | WI67_01675 | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. | 0.904 |
| AOI83311.1 | hemC | WI67_13105 | WI67_13110 | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
| AOI83311.1 | hemE | WI67_13105 | WI67_00665 | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.948 |
| AOI84130.1 | AOI83311.1 | WI67_08255 | WI67_13105 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.926 |
| AOI84130.1 | AOI87158.1 | WI67_08255 | WI67_25400 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.908 |
| AOI84130.1 | CobI | WI67_08255 | WI67_08365 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Precorrin-2 C(20)-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | 0.922 |
| AOI84130.1 | cysG_2 | WI67_08255 | WI67_13335 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. | 0.919 |
| AOI84130.1 | cysH | WI67_08255 | WI67_13350 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Uses adenylyl sulfate as substrate and thioredoxin as electron donor. Belongs to the PAPS reductase family. CysH subfamily. | 0.749 |
| AOI84130.1 | hemA_2 | WI67_08255 | WI67_02295 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.782 |
| AOI84130.1 | hemB | WI67_08255 | WI67_01675 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. | 0.864 |
| AOI84130.1 | hemC | WI67_08255 | WI67_13110 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.986 |
| AOI84130.1 | hemE | WI67_08255 | WI67_00665 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.918 |
| AOI85770.1 | AOI87158.1 | WI67_25410 | WI67_25400 | Nitrate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.724 |
| AOI87158.1 | AOI83311.1 | WI67_25400 | WI67_13105 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.926 |
| AOI87158.1 | AOI84130.1 | WI67_25400 | WI67_08255 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.908 |
