STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABF65743.1L-threonine ammonia-lyase. (317 aa)    
Predicted Functional Partners:
ABF63607.1
Acetolactate synthase, small subunit.
  
 
 0.955
ABF65062.1
L-threonine synthase.
  
 
 0.946
ABF64665.1
Acetolactate synthase, large subunit; Belongs to the TPP enzyme family.
 
 0.933
trpB
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.929
ilvA
L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
  
 
0.924
ABF63608.1
Acetolactate synthase, large subunit.
  
 0.923
ABF64263.1
Thiamine pyrophosphate enzyme-like TPP-binding; Belongs to the TPP enzyme family.
  
 0.923
ABF65432.1
Pyridoxal-5'-phosphate-dependent enzyme beta subunit.
  
  
 
0.923
ABF64694.1
L-serine ammonia-lyase / 2-hydroxymethylglutarate dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.920
trpA
Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 
 0.919
Your Current Organism:
Ruegeria sp. TM1040
NCBI taxonomy Id: 292414
Other names: R. sp. TM1040, Silicibacter sp. TM1040
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