node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tbd_0058 | Tbd_0471 | Tbd_0058 | Tbd_0471 | Ribonucleoside-diphosphate reductase alpha chain; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Metal dependent phosphohydrolase, HD region; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |
Tbd_0058 | Tbd_1976 | Tbd_0058 | Tbd_1976 | Ribonucleoside-diphosphate reductase alpha chain; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Ribonucleoside-diphosphate reductase alpha chain; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.915 |
Tbd_0058 | gmk | Tbd_0058 | Tbd_0473 | Ribonucleoside-diphosphate reductase alpha chain; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.912 |
Tbd_0058 | guaA | Tbd_0058 | Tbd_1751 | Ribonucleoside-diphosphate reductase alpha chain; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.534 |
Tbd_0058 | ndk | Tbd_0058 | Tbd_0590 | Ribonucleoside-diphosphate reductase alpha chain; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.915 |
Tbd_0058 | pykA | Tbd_0058 | Tbd_0162 | Ribonucleoside-diphosphate reductase alpha chain; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.904 |
Tbd_0471 | Tbd_0058 | Tbd_0471 | Tbd_0058 | Metal dependent phosphohydrolase, HD region; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonucleoside-diphosphate reductase alpha chain; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.900 |
Tbd_0471 | Tbd_0474 | Tbd_0471 | Tbd_0474 | Metal dependent phosphohydrolase, HD region; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Conserved hypothetical protein. | 0.713 |
Tbd_0471 | Tbd_1976 | Tbd_0471 | Tbd_1976 | Metal dependent phosphohydrolase, HD region; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonucleoside-diphosphate reductase alpha chain; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.900 |
Tbd_0471 | gmk | Tbd_0471 | Tbd_0473 | Metal dependent phosphohydrolase, HD region; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.977 |
Tbd_0471 | ndk | Tbd_0471 | Tbd_0590 | Metal dependent phosphohydrolase, HD region; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.914 |
Tbd_0471 | pykA | Tbd_0471 | Tbd_0162 | Metal dependent phosphohydrolase, HD region; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.916 |
Tbd_0471 | rpoZ | Tbd_0471 | Tbd_0472 | Metal dependent phosphohydrolase, HD region; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.865 |
Tbd_0474 | Tbd_0471 | Tbd_0474 | Tbd_0471 | Conserved hypothetical protein. | Metal dependent phosphohydrolase, HD region; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.713 |
Tbd_0474 | gmk | Tbd_0474 | Tbd_0473 | Conserved hypothetical protein. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.953 |
Tbd_0474 | rpoZ | Tbd_0474 | Tbd_0472 | Conserved hypothetical protein. | RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.833 |
Tbd_0777 | gmk | Tbd_0777 | Tbd_0473 | Hypoxanthine phosphoribosyltransferase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.940 |
Tbd_0777 | guaA | Tbd_0777 | Tbd_1751 | Hypoxanthine phosphoribosyltransferase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.951 |
Tbd_0777 | surE | Tbd_0777 | Tbd_0835 | Hypoxanthine phosphoribosyltransferase. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
Tbd_1976 | Tbd_0058 | Tbd_1976 | Tbd_0058 | Ribonucleoside-diphosphate reductase alpha chain; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Ribonucleoside-diphosphate reductase alpha chain; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.915 |