STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tbd_0983Adenylyl cyclase class-3/4/guanylyl cyclase. (737 aa)    
Predicted Functional Partners:
Tbd_0984
cAMP phosphodiesterase class-II.
 
   
 0.943
Tbd_0671
Putative Adenylate/Guanylate Cyclase.
 
  
0.941
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.917
pykA
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.901
Tbd_0471
Metal dependent phosphohydrolase, HD region; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.900
Tbd_1758
GTP diphosphokinase, RelA/SpoT protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.900
Tbd_2171
Ribonucleotide reductase.
     
  0.900
Tbd_1570
Cyclic nucleotide-binding domain (cNMP-BD) protein.
 
 
 0.839
Tbd_0982
Putative Zn-dependent protease containing TPR repeats.
      0.836
Tbd_0981
Hypothetical protein.
       0.818
Your Current Organism:
Thiobacillus denitrificans ATCC 25259
NCBI taxonomy Id: 292415
Other names: T. denitrificans ATCC 25259, Thiobacillus denitrificans str. ATCC 25259, Thiobacillus denitrificans strain ATCC 25259
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.