node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tbd_0221 | Tbd_1162 | Tbd_0221 | Tbd_1162 | Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | Serine O-acetyltransferase. | 0.810 |
Tbd_0843 | Tbd_1162 | Tbd_0843 | Tbd_1162 | Homoserine dehydrogenase. | Serine O-acetyltransferase. | 0.825 |
Tbd_0843 | ilvA | Tbd_0843 | Tbd_2363 | Homoserine dehydrogenase. | Threonine dehydratase I; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.563 |
Tbd_0964 | Tbd_1162 | Tbd_0964 | Tbd_1162 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Serine O-acetyltransferase. | 0.997 |
Tbd_0964 | cysS | Tbd_0964 | Tbd_1902 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Cysteinyl-tRNA synthetase, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.923 |
Tbd_1162 | Tbd_0221 | Tbd_1162 | Tbd_0221 | Serine O-acetyltransferase. | Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.810 |
Tbd_1162 | Tbd_0843 | Tbd_1162 | Tbd_0843 | Serine O-acetyltransferase. | Homoserine dehydrogenase. | 0.825 |
Tbd_1162 | Tbd_0964 | Tbd_1162 | Tbd_0964 | Serine O-acetyltransferase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.997 |
Tbd_1162 | Tbd_1482 | Tbd_1162 | Tbd_1482 | Serine O-acetyltransferase. | CDP-diacylglycerol-serine o-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.800 |
Tbd_1162 | Tbd_2002 | Tbd_1162 | Tbd_2002 | Serine O-acetyltransferase. | Hypothetical protein. | 0.897 |
Tbd_1162 | cysS | Tbd_1162 | Tbd_1902 | Serine O-acetyltransferase. | Cysteinyl-tRNA synthetase, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.989 |
Tbd_1162 | glyA | Tbd_1162 | Tbd_2165 | Serine O-acetyltransferase. | Glycine/serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.842 |
Tbd_1162 | ilvA | Tbd_1162 | Tbd_2363 | Serine O-acetyltransferase. | Threonine dehydratase I; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.810 |
Tbd_1162 | trpA | Tbd_1162 | Tbd_1913 | Serine O-acetyltransferase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.810 |
Tbd_1162 | trpB-2 | Tbd_1162 | Tbd_1914 | Serine O-acetyltransferase. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.810 |
Tbd_1482 | Tbd_1162 | Tbd_1482 | Tbd_1162 | CDP-diacylglycerol-serine o-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Serine O-acetyltransferase. | 0.800 |
Tbd_1482 | glyA | Tbd_1482 | Tbd_2165 | CDP-diacylglycerol-serine o-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Glycine/serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.900 |
Tbd_1482 | ilvA | Tbd_1482 | Tbd_2363 | CDP-diacylglycerol-serine o-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Threonine dehydratase I; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.900 |
Tbd_1482 | trpA | Tbd_1482 | Tbd_1913 | CDP-diacylglycerol-serine o-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.900 |
Tbd_1482 | trpB-2 | Tbd_1482 | Tbd_1914 | CDP-diacylglycerol-serine o-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |