STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tbd_2091Peptidase S1C, Do; Belongs to the peptidase S1C family. (464 aa)    
Predicted Functional Partners:
Tbd_2094
Hypothetical protein.
  
 
 0.941
Tbd_2092
Putative positive regulator of sigma E activity.
  
  
 0.824
Tbd_2093
Putative Sigma E regulatory protein, MucB/RseB.
  
  
 0.812
Tbd_2095
Sigma-24 (FecI); Belongs to the sigma-70 factor family. ECF subfamily.
     
 0.807
Tbd_2090
Conserved hypothetical protein.
  
   0.798
Tbd_2088
Peptidase S26A, signal peptidase I; Belongs to the peptidase S26 family.
 
   
 0.708
lepA
GTPase LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
    
 0.682
era
GTPase; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
   
 
 0.599
Tbd_1268
Multi-sensor Hybrid Histidine Kinase.
  
  
 0.581
Tbd_2671
Periplasmic Sensor Hybrid Histidine Kinase.
  
  
 0.581
Your Current Organism:
Thiobacillus denitrificans ATCC 25259
NCBI taxonomy Id: 292415
Other names: T. denitrificans ATCC 25259, Thiobacillus denitrificans str. ATCC 25259, Thiobacillus denitrificans strain ATCC 25259
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.